2g3y: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2g3y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G3Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[2g3y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G3Y FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rap|2rap]], [[1kao|1kao]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2rap|2rap]], [[1kao|1kao]]</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GEM, KIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GEM, KIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g3y RCSB], [http://www.ebi.ac.uk/pdbsum/2g3y PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g3y RCSB], [http://www.ebi.ac.uk/pdbsum/2g3y PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/GEM_HUMAN GEM_HUMAN]] Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith, C]]
[[Category: Berridge, G.]]
[[Category: Berridge, G]]
[[Category: Bray, J.]]
[[Category: Bray, J]]
[[Category: Burgess, N.]]
[[Category: Burgess, N]]
[[Category: Delft, F von.]]
[[Category: Delft, F von]]
[[Category: Doyle, D.]]
[[Category: Doyle, D]]
[[Category: Edwards, A.]]
[[Category: Edwards, A]]
[[Category: Elkins, J.]]
[[Category: Elkins, J]]
[[Category: Fedorov, O.]]
[[Category: Fedorov, O]]
[[Category: Gileadi, C.]]
[[Category: Gileadi, C]]
[[Category: Lee, W H.]]
[[Category: Lee, W H]]
[[Category: Pantic, N.]]
[[Category: Pantic, N]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Schoch, G.]]
[[Category: Schoch, G]]
[[Category: Sobott, F.]]
[[Category: Sobott, F]]
[[Category: Soundararajan, M.]]
[[Category: Soundararajan, M]]
[[Category: Sundstrom, M.]]
[[Category: Sundstrom, M]]
[[Category: Turnbull, A.]]
[[Category: Turnbull, A]]
[[Category: Ugochukwu, E.]]
[[Category: Ugochukwu, E]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Gdp]]
[[Category: Gdp]]
[[Category: Gem]]
[[Category: Gem]]
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[[Category: Signaling protein]]
[[Category: Signaling protein]]
[[Category: Small gtpase]]
[[Category: Small gtpase]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]

Revision as of 14:33, 25 December 2014

Crystal structure of the human small GTPase GEMCrystal structure of the human small GTPase GEM

Structural highlights

2g3y is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:GEM, KIR (Homo sapiens)
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[GEM_HUMAN] Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2g3y, resolution 2.40Å

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OCA