2f0s: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f0s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F0S FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f0s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F0S FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ey0|1ey0]], [[2exz|2exz]], [[2ey1|2ey1]], [[2ey2|2ey2]], [[2ey5|2ey5]], [[2ey6|2ey6]], [[2eyf|2eyf]], [[2eyh|2eyh]], [[2eyj|2eyj]], [[2eyl|2eyl]], [[2eym|2eym]], [[2eyo|2eyo]], [[2eyp|2eyp]], [[2f0d|2f0d]], [[2f0e|2f0e]], [[2f0f|2f0f]], [[2f0g|2f0g]], [[2f0h|2f0h]], [[2f0i|2f0i]], [[2f0j|2f0j]], [[2f0k|2f0k]], [[2f0l|2f0l]], [[2f0m|2f0m]], [[2f0n|2f0n]], [[2f0o|2f0o]], [[2f0p|2f0p]], [[2f0q|2f0q]], [[2f0t|2f0t]], [[2f0u|2f0u]], [[2f0v|2f0v]], [[2f0w|2f0w]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ey0|1ey0]], [[2exz|2exz]], [[2ey1|2ey1]], [[2ey2|2ey2]], [[2ey5|2ey5]], [[2ey6|2ey6]], [[2eyf|2eyf]], [[2eyh|2eyh]], [[2eyj|2eyj]], [[2eyl|2eyl]], [[2eym|2eym]], [[2eyo|2eyo]], [[2eyp|2eyp]], [[2f0d|2f0d]], [[2f0e|2f0e]], [[2f0f|2f0f]], [[2f0g|2f0g]], [[2f0h|2f0h]], [[2f0i|2f0i]], [[2f0j|2f0j]], [[2f0k|2f0k]], [[2f0l|2f0l]], [[2f0m|2f0m]], [[2f0n|2f0n]], [[2f0o|2f0o]], [[2f0p|2f0p]], [[2f0q|2f0q]], [[2f0t|2f0t]], [[2f0u|2f0u]], [[2f0v|2f0v]], [[2f0w|2f0w]]</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f0s RCSB], [http://www.ebi.ac.uk/pdbsum/2f0s PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f0s RCSB], [http://www.ebi.ac.uk/pdbsum/2f0s PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Micrococcal nuclease]]
[[Category: Micrococcal nuclease]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Lu, J Z.]]
[[Category: Lu, J Z]]
[[Category: Sakon, J.]]
[[Category: Sakon, J]]
[[Category: Stites, W E.]]
[[Category: Stites, W E]]
[[Category: Calcium]]
[[Category: Calcium]]
[[Category: Dna hydrolase]]
[[Category: Dna hydrolase]]

Revision as of 09:57, 24 December 2014

Crystal structure of Staphylococcal nuclease mutant V66L/I92VCrystal structure of Staphylococcal nuclease mutant V66L/I92V

Structural highlights

2f0s is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:nuc (Staphylococcus aureus)
Activity:Micrococcal nuclease, with EC number 3.1.31.1
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2f0s, resolution 1.75Å

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