1k0o: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1k0o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K0O FirstGlance]. <br> | <table><tr><td colspan='2'>[[1k0o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K0O FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k0o RCSB], [http://www.ebi.ac.uk/pdbsum/1k0o PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k0o RCSB], [http://www.ebi.ac.uk/pdbsum/1k0o PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN]] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bauskin, A R | [[Category: Bauskin, A R]] | ||
[[Category: Breit, S N | [[Category: Breit, S N]] | ||
[[Category: Campbell, T J | [[Category: Campbell, T J]] | ||
[[Category: Curmi, P M.G | [[Category: Curmi, P M.G]] | ||
[[Category: DeMaere, M Z | [[Category: DeMaere, M Z]] | ||
[[Category: Fairlie, W D | [[Category: Fairlie, W D]] | ||
[[Category: Harrop, S J | [[Category: Harrop, S J]] | ||
[[Category: Jankova, L | [[Category: Jankova, L]] | ||
[[Category: Mazzanti, M | [[Category: Mazzanti, M]] | ||
[[Category: Pankhurst, S | [[Category: Pankhurst, S]] | ||
[[Category: Qiu, M R | [[Category: Qiu, M R]] | ||
[[Category: Reztsova, T | [[Category: Reztsova, T]] | ||
[[Category: Tonini, R | [[Category: Tonini, R]] | ||
[[Category: Valenzuela, S M | [[Category: Valenzuela, S M]] | ||
[[Category: Warton, K | [[Category: Warton, K]] | ||
[[Category: Wu, W M | [[Category: Wu, W M]] | ||
[[Category: Chloride ion channel]] | [[Category: Chloride ion channel]] | ||
[[Category: Clic1]] | [[Category: Clic1]] | ||