1jxt: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jxt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crambe_hispanica_subsp._abyssinica Crambe hispanica subsp. abyssinica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JXT FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jxt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crambe_hispanica_subsp._abyssinica Crambe hispanica subsp. abyssinica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JXT FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1crn|1crn]], [[1cnr|1cnr]], [[1ab1|1ab1]], [[1cbn|1cbn]], [[1jxu|1jxu]], [[1jxw|1jxw]], [[1jxx|1jxx]], [[1jxy|1jxy]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1crn|1crn]], [[1cnr|1cnr]], [[1ab1|1ab1]], [[1cbn|1cbn]], [[1jxu|1jxu]], [[1jxw|1jxw]], [[1jxx|1jxx]], [[1jxy|1jxy]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jxt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jxt RCSB], [http://www.ebi.ac.uk/pdbsum/1jxt PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jxt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jxt RCSB], [http://www.ebi.ac.uk/pdbsum/1jxt PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CRAM_CRAAB CRAM_CRAAB]] The function of this hydrophobic plant seed protein is not known. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Crambe hispanica subsp. abyssinica]] | [[Category: Crambe hispanica subsp. abyssinica]] | ||
[[Category: Mohanty, U | [[Category: Mohanty, U]] | ||
[[Category: Stec, B | [[Category: Stec, B]] | ||
[[Category: Teeter, M M | [[Category: Teeter, M M]] | ||
[[Category: Yamano, A | [[Category: Yamano, A]] | ||
[[Category: Function]] | [[Category: Function]] | ||
[[Category: Plant protein]] | [[Category: Plant protein]] | ||
[[Category: Substate]] | [[Category: Substate]] | ||
[[Category: Water]] | [[Category: Water]] | ||
Revision as of 17:36, 24 December 2014
CRAMBIN MIXED SEQUENCE FORM AT 160 K. PROTEIN/WATER SUBSTATESCRAMBIN MIXED SEQUENCE FORM AT 160 K. PROTEIN/WATER SUBSTATES
Structural highlights
Function[CRAM_CRAAB] The function of this hydrophobic plant seed protein is not known. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMedDiverse biochemical and biophysical experiments indicate that all proteins, regardless of size or origin, undergo a dynamic transition near 200 K. The cause of this shift in dynamic behavior, termed a "glass transition," and its relation to protein function are important open questions. One explanation postulated for the transition is solidification of correlated motions in proteins below the transition. We verified this conjecture by showing that crambin's radius of gyration (Rg) remains constant below approximately 180 K. We show that both atom position and dynamics of protein and solvent are physically coupled, leading to a novel cooperative state. This glassy state is identified by negative slopes of the Debye-Waller (B) factor vs. temperature. It is composed of multisubstate side chains and solvent. Based on generalization of Adam-Gibbs' notion of a cooperatively rearranging region and decrease of the total entropy with temperature, we calculate the slope of the Debye-Waller factor. The results are in accord with experiment. On the nature of a glassy state of matter in a hydrated protein: Relation to protein function.,Teeter MM, Yamano A, Stec B, Mohanty U Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11242-7. PMID:11572978[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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