Potassium channel Xavier: Difference between revisions
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* Entering the hydrophobic pocket | * Entering the hydrophobic pocket | ||
* | * Aqueous cavity and desolvation | ||
* Selectivity filter | * Selectivity filter | ||
* Explaining the voltage sensor and closing/opening of channel | * Explaining the voltage sensor and closing/opening of channel | ||
==== Entering the hydrophobic pocket ==== | |||
It is important to notice that with the exception of the selectivity filter the pore lining is <scene name='Potassium_Channel/Full_pore_hdryo/2'>mainly hydrophobic</scene>. | |||
The entrance of the channel, at the bottom of the 34Å pore containing transmembrane region lies a number of <scene name='Potassium_Channel/High_filter_aromatic/2'>aromatic residues</scene> which help form a seal between the pore and the intracellular cytoplasm. | |||
==== Aqueous cavity and desolvation ==== | |||
This hydrophobic lining provides an inert surface over which the diffusing ion can slide unimpaired. At the end of the hydrophobic porus there is an <scene name='Potassium_Channel/Full_pore_h20/1'>aqueous cavity</scene> (<scene name='Potassium_Channel/Full_pore_h20_spin/1'>Spinning Model</scene>). At this point, K<sup>+</sup> ions find a position of hydration and get ready to be dehydrated and get into the selectivity filter. | |||
====Selectivity Filter and Pore==== | ====Selectivity Filter and Pore==== | ||