Phosphoglycerate dehydrogenase: Difference between revisions
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==3D structures of phosphoglycerate dehydrogenase== | ==3D structures of phosphoglycerate dehydrogenase== | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | |||
*'''Phosphoglycerate dehydrogenase''' | |||
[[1ygy]], [[3dc2]] – MtPGDH – ''Mycobacterium tuberculosis''<br /> | **[[1ygy]], [[3dc2]] – MtPGDH – ''Mycobacterium tuberculosis''<br /> | ||
[[3evt]] - PGDH – ''Lactobacillus plantarum''<br /> | **[[3evt]] - PGDH – ''Lactobacillus plantarum''<br /> | ||
[[3gg9]] - PGDH – ''Ralstonia solanacearum''<br /> | **[[3gg9]] - PGDH – ''Ralstonia solanacearum''<br /> | ||
[[3k5p]] - PGDH (mutant) – ''Brucella melitensis'' | **[[3k5p]] - PGDH (mutant) – ''Brucella melitensis'' | ||
*Phosphoglycerate dehydrogenase binary complex | |||
[[1sc6]], [[2p9c]], [[2p9e]], [[2p9g]] - EcPGDH (mutant) + NAD – ''Escherichia coli''<br /> | **[[1sc6]], [[2p9c]], [[2p9e]], [[2p9g]] - EcPGDH (mutant) + NAD – ''Escherichia coli''<br /> | ||
[[1yba]] - EcPGDH + NAD<br /> | **[[1yba]] - EcPGDH + NAD<br /> | ||
[[1wwk]] - PGDH + NAD – ''Pyrococcus horikoshii''<br /> | **[[1wwk]] - PGDH + NAD – ''Pyrococcus horikoshii''<br /> | ||
[[2g76]] - PGDH + NAD – human<br /> | **[[2g76]] - PGDH + NAD – human<br /> | ||
[[2ekl]] - PGDH + NAD – ''Sulfolobus tokodaii''<br /> | **[[2ekl]] - PGDH + NAD – ''Sulfolobus tokodaii''<br /> | ||
[[3ddn]] - MtPGDH + hydroxypyruvic acid phosphate | **[[3ddn]] - MtPGDH + hydroxypyruvic acid phosphate | ||
*Phosphoglycerate dehydrogenase ternary complex | |||
**[[1psd]] - EcPGDH + serine + NAD <br /> | |||
**[[2pa3]] - EcPGDH (mutant) + serine + NAD | |||
}} | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:55, 3 December 2014
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Phosphoglycerate dehydrogenase (PGDH) catalyzes the conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate. This is the first step of serine biosynthesis. NAD is used as cofactor. In some cancer cells there is an elevation in PGDH level.