Villin: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
Line 1: | Line 1: | ||
{{STRUCTURE_2k6n| right| PDB=2k6n | SCENE=Villin/Cv/1 |CAPTION=Human supervillin headpiece, [[2k6n]] }} | {{STRUCTURE_2k6n| right| PDB=2k6n | SCENE=Villin/Cv/1 |CAPTION=Human supervillin headpiece, [[2k6n]] }} | ||
[[Villin]] (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin<ref>PMID:10480879</ref>. '''Supervillin (SVIL)''' contains numerous gelsolin-like domains in its C-terminal and interacts with actin. '''Advillin (AVIL)''' is another actin-binding protein in the [[gelsolin]] superfamily which is expressed in the peripheral sensory neurons. '''Cytovillin (CVIL) or ezrin or villin-2''' serves as intermediate between plasma membrane and actin cytoskeleton. | * [[Villin]] (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin<ref>PMID:10480879</ref>.<br /> | ||
* '''Supervillin (SVIL)''' contains numerous gelsolin-like domains in its C-terminal and interacts with actin.<br /> | |||
* '''Advillin (AVIL)''' is another actin-binding protein in the [[gelsolin]] superfamily which is expressed in the peripheral sensory neurons.<br /> | |||
* '''Cytovillin (CVIL) or ezrin or villin-2''' serves as intermediate between plasma membrane and actin cytoskeleton. | |||
== 3D Structures of Villin == | == 3D Structures of Villin == |