Quinone reductase: Difference between revisions
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<StructureSection load='2f1o.pdb' size='450' scene='2f1o/Com_view/2' caption='NADPH dehydrogenase complex with FAD (red) and dicoumarol (blue) [[2f1o]]'> | <StructureSection load='2f1o.pdb' size='450' scene='2f1o/Com_view/2' caption='NADPH dehydrogenase complex with FAD (red) and dicoumarol (blue) [[2f1o]]'> | ||
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'''Quinone reductase type 1 (QR1)''' reduces quinines to the non-toxic hydroquinone. '''Quinone reductase type 2 (QR2)''' catalyzes the reduction of adrenochrome. The '''sulfide-quinone reductase (SQR)''' reduces sulfide and thus provides electrons for phototropic processes in bacteria. '''NADPH-quinone reductase (NQR)''' catalyzes the reduction of quinone to semiquinone. The images at the left and at the right correspond to one representative Quinone reductase, ''i.e.'' the crystal structure of NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol ([[2f1o]]). | '''Quinone reductase type 1 (QR1)''' reduces quinines to the non-toxic hydroquinone. '''Quinone reductase type 2 (QR2)''' catalyzes the reduction of adrenochrome. The '''sulfide-quinone reductase (SQR)''' reduces sulfide and thus provides electrons for phototropic processes in bacteria. '''NADPH-quinone reductase (NQR)''' catalyzes the reduction of quinone to semiquinone. The images at the left and at the right correspond to one representative Quinone reductase, ''i.e.'' the crystal structure of NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol ([[2f1o]]). | ||
== NADH Quinone oxidoreductase type 1 (NQO1) in complex with its potent inhibitor dicoumarol == | == NADH Quinone oxidoreductase type 1 (NQO1) in complex with its potent inhibitor dicoumarol == | ||