Adenylate kinase: Difference between revisions
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[[Adenylate kinase]] (ADK, EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.3 2.7.4.3]) is a phosphotransferase which catalyzes the interconversion of ADP to ATP+AMP. ADK is important in cellular energy homeostasis. Dinucleotides polyphosphates like diadenosine pentaphosphate | [[Adenylate kinase]] (ADK, EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.3 2.7.4.3]) is a phosphotransferase which catalyzes the interconversion of ADP to ATP+AMP. ADK is important in cellular energy homeostasis. Dinucleotides polyphosphates like diadenosine pentaphosphate | ||
(AP5) inhibit ADK. The images at the left and at the right correspond to one representative ADK, ''i.e.'' the crystal structure of Adenylate kinase from ''Desulfovibrio gigas'' ([[3l0p]]). | (AP5) inhibit ADK. The images at the left and at the right correspond to one representative ADK, ''i.e.'' the crystal structure of Adenylate kinase from ''Desulfovibrio gigas'' ([[3l0p]]). | ||
Adenylate kinase is an essential catalyst for cellular growth and multiplication. ADK belongs to a family of enzymes essential to life, and is highly abundant inside the cell. It is involved in the reversible transfer of the terminal phosphate group from Mg2+ATP to Mg2+AMP with high energy turnover: Mg2+ATP + AMP↔Mg2+ADP + ADP. | Adenylate kinase is an essential catalyst for cellular growth and multiplication. ADK belongs to a family of enzymes essential to life, and is highly abundant inside the cell. It is involved in the reversible transfer of the terminal phosphate group from Mg2+ATP to Mg2+AMP with high energy turnover: Mg2+ATP + AMP↔Mg2+ADP + ADP. | ||
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</StructureSection> | </StructureSection> | ||
== 3D Structures of Adenylate kinase == | == 3D Structures of Adenylate kinase == | ||