197d: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[197d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=197D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=197D FirstGlance]. <br> | <table><tr><td colspan='2'>[[197d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=197D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=197D FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=197d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=197d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=197d RCSB], [http://www.ebi.ac.uk/pdbsum/197d PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=197d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=197d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=197d RCSB], [http://www.ebi.ac.uk/pdbsum/197d PDBsum]</span></td></tr> | ||
<table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Courseille, C | [[Category: Courseille, C]] | ||
[[Category: Dautant, A | [[Category: Dautant, A]] | ||
[[Category: Estaintot, B Langlois D | [[Category: Estaintot, B Langlois D]] | ||
[[Category: Precigoux, G | [[Category: Precigoux, G]] | ||
[[Category: A-dna]] | [[Category: A-dna]] | ||
[[Category: Dna]] | [[Category: Dna]] | ||
[[Category: Double helix]] | [[Category: Double helix]] | ||
Revision as of 13:59, 22 December 2014
ORTHORHOMBIC CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GTACGTAC). COMPARISON WITH THE TETRAGONAL STRUCTUREORTHORHOMBIC CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GTACGTAC). COMPARISON WITH THE TETRAGONAL STRUCTURE
Structural highlights
Publication Abstract from PubMedThe X-ray crystal structure of the double-helical A-DNA octanucleotide d(GTACGTAC) has been solved by molecular replacement and refined to a resolution of 0.219 nm. The final R-factor is equal to 16.1% for 1516 observed reflections with F > 4 sigma(F). The sequence crystallizes as an A-DNA-type double helix in the orthorhombic space group P2(1)2(1)2, with one duplex molecule solvated by 66 water molecules in the asymmetric unit. Cell parameters are a = 3.860 nm, b = 5.082 nm, c = 2.174 nm. It is the first time that such a crystal form has been observed. This orthorhombic structure has been compared with the tetragonal structure of the same oligonucleotide. It adopts a bent structure with an unusual packing between symmetry-related molecules. Orthorhombic crystal structure of the A-DNA octamer d(GTACGTAC). Comparison with the tetragonal structure.,Langlois d'Estaintot B, Dautant A, Courseille C, Precigoux G Eur J Biochem. 1993 Apr 15;213(2):673-82. PMID:8477741[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References |
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