Inosine monophosphate dehydrogenase: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='4fo4' size='380' side='right' caption='Structure of IMPDH complex with inosinic acid and the inhibitor mycophenolic acid (PDB code 4fo4).' scene=''> == Functi... |
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<StructureSection load='4fo4' size='380' side='right' caption='Structure of IMPDH complex with inosinic acid, K+ (purple) and the inhibitor mycophenolic acid (PDB code [[4fo4]]).' scene=''> | |||
<StructureSection load='4fo4' size='380' side='right' caption='Structure of IMPDH complex with inosinic acid and the inhibitor mycophenolic acid (PDB code [[4fo4]]).' scene=''> | |||
== Function == | == Function == | ||
'''Inosine monophosphate dehydrogenase''' (IMPDH) is part of the GTP biosynthesis and catalyzes the conversion of inosine monophosphate to xanthosine monophosphate while reducing NAD. IMPDH is inhibited by | '''Inosine monophosphate dehydrogenase''' (IMPDH) is part of the GTP biosynthesis and catalyzes the conversion of inosine monophosphate to xanthosine monophosphate while reducing NAD. IMPDH is inhibited by ribavirin and mycophenolic acid. | ||
== Disease == | == Disease == | ||