4bpv: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4bpv]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BPV FirstGlance]. <br> | <table><tr><td colspan='2'>[[4bpv]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BPV FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OFH:(4R)-4-[(2-CHLORO-4-{[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]OXY}PHENYL)SULFONYL]-N-{1-[(E)-IMINOMETHYL]CYCLOPROPYL}-1-{[1-(TRIFLUOROMETHYL)CYCLOPROPYL]CARBONYL}-L-PROLINAMIDE'>OFH</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OFH:(4R)-4-[(2-CHLORO-4-{[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]OXY}PHENYL)SULFONYL]-N-{1-[(E)-IMINOMETHYL]CYCLOPROPYL}-1-{[1-(TRIFLUOROMETHYL)CYCLOPROPYL]CARBONYL}-L-PROLINAMIDE'>OFH</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bpv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bpv RCSB], [http://www.ebi.ac.uk/pdbsum/4bpv PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bpv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bpv RCSB], [http://www.ebi.ac.uk/pdbsum/4bpv PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CATS_MOUSE CATS_MOUSE]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cathepsin S]] | [[Category: Cathepsin S]] | ||
[[Category: Banner, D W | [[Category: Banner, D W]] | ||
[[Category: Benz, J | [[Category: Benz, J]] | ||
[[Category: Gsell, B | [[Category: Gsell, B]] | ||
[[Category: Haap, W | [[Category: Haap, W]] | ||
[[Category: Ruf, A | [[Category: Ruf, A]] | ||
[[Category: Stihle, M | [[Category: Stihle, M]] | ||
[[Category: Covalent ligand]] | [[Category: Covalent ligand]] | ||
[[Category: Cysteine protease]] | [[Category: Cysteine protease]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 20:58, 25 December 2014
MOUSE CATHEPSIN S WITH COVALENT LIGANDMOUSE CATHEPSIN S WITH COVALENT LIGAND
Structural highlights
Function[CATS_MOUSE] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. |
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