Tumor necrosis factor receptor: Difference between revisions
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Michal Harel (talk | contribs) No edit summary |
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== Function == | == Function == | ||
'''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains. TNFRSF 6 is called '''Fas'''; TNFRSF 10B is called '''Dr5'''; TNFRSF 21 is called '''Dr6'''; TNFRSF 11A is called '''RANK'''; | '''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains. TNFRSF 6 is called '''Fas'''; TNFRSF 10B is called '''Dr5'''; TNFRSF 21 is called '''Dr6'''; TNFRSF 11A is called '''RANK'''; TNFRSF 18 is called '''GITRL'''. | ||
== Disease == | == Disease == | ||
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[[2rpj]] – hTNFRSF-12A cysteine-rich domain – NMR <br /> | [[2rpj]] – hTNFRSF-12A cysteine-rich domain – NMR <br /> | ||
'''TNFRSF-18''' | '''TNFRSF-18 (GITRL)''' | ||
[[4db5]] – TNFRSF-18 – rabbit <br /> | [[4db5]] – TNFRSF-18 – rabbit <br /> | ||