237d: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[237d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=237D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=237D FirstGlance]. <br> | <table><tr><td colspan='2'>[[237d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=237D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=237D FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=237d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=237d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=237d RCSB], [http://www.ebi.ac.uk/pdbsum/237d PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=237d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=237d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=237d RCSB], [http://www.ebi.ac.uk/pdbsum/237d PDBsum]</span></td></tr> | ||
<table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Berman, H M | [[Category: Berman, H M]] | ||
[[Category: Neidle, S | [[Category: Neidle, S]] | ||
[[Category: Nunn, C M | [[Category: Nunn, C M]] | ||
[[Category: Spink, N | [[Category: Spink, N]] | ||
[[Category: Vojtechovsky, J | [[Category: Vojtechovsky, J]] | ||
[[Category: B-dna]] | [[Category: B-dna]] | ||
[[Category: Dna]] | [[Category: Dna]] | ||
Revision as of 09:17, 22 December 2014
CRYSTAL STRUCTURE OF A DNA DECAMER SHOWING A NOVEL PSEUDO FOUR-WAY HELIX-HELIX JUNCTIONCRYSTAL STRUCTURE OF A DNA DECAMER SHOWING A NOVEL PSEUDO FOUR-WAY HELIX-HELIX JUNCTION
Structural highlights
Publication Abstract from PubMedThe crystal structure of the decanucleotide d(CGCAATTGCG)2 has been solved by a combination of molecular replacement and heavy-atom procedures and has been refined to an R factor of 20.2% at 2.7 A. It is not a fully base-paired duplex but has a central core of eight Watson-Crick base pairs flanked by unpaired terminal guanosines and cytosines. These participate in hydrogen-bonding arrangements with adjacent decamer duplexes in the crystal lattice. The unpaired guanosines are bound in the G+C regions of duplex minor grooves. The cytosines have relatively high mobility, even though they are constrained to be in one region where they are involved in base-paired triplets with G.C base pairs. The 5'-AATT sequence in the duplex region has a narrow minor groove, providing further confirmation of the sequence-dependent nature of groove width. Crystal structure of a DNA decamer showing a novel pseudo four-way helix-helix junction.,Spink N, Nunn CM, Vojtechovsky J, Berman HM, Neidle S Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10767-71. PMID:7479880[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References |
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