4e7d: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4e7d]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Entcc Entcc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E7D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E7D FirstGlance]. <br>
<table><tr><td colspan='2'>[[4e7d]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Entcc Entcc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E7D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E7D FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e7b|4e7b]], [[4e7c|4e7c]], [[4e7e|4e7e]], [[4e7f|4e7f]], [[4e7g|4e7g]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e7b|4e7b]], [[4e7c|4e7c]], [[4e7e|4e7e]], [[4e7f|4e7f]], [[4e7g|4e7g]]</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECL_04571, murA, murZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=716541 ENTCC])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECL_04571, murA, murZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=716541 ENTCC])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e7d RCSB], [http://www.ebi.ac.uk/pdbsum/4e7d PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e7d RCSB], [http://www.ebi.ac.uk/pdbsum/4e7d PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/MURA_ENTCC MURA_ENTCC]] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.


==See Also==
==See Also==
Line 17: Line 19:
[[Category: Entcc]]
[[Category: Entcc]]
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
[[Category: Schonbrunn, E.]]
[[Category: Schonbrunn, E]]
[[Category: Yang, Y.]]
[[Category: Yang, Y]]
[[Category: Zhu, J Y.]]
[[Category: Zhu, J Y]]
[[Category: Biogenesis/degradation]]
[[Category: Biogenesis/degradation]]
[[Category: Cell wall]]
[[Category: Cell wall]]

Revision as of 00:21, 25 December 2014

E. cloacae MurA in complex with UDPE. cloacae MurA in complex with UDP

Structural highlights

4e7d is a 4 chain structure with sequence from Entcc. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
NonStd Res:
Gene:ECL_04571, murA, murZ (ENTCC)
Activity:UDP-N-acetylglucosamine 1-carboxyvinyltransferase, with EC number 2.5.1.7
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[MURA_ENTCC] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.

See Also

4e7d, resolution 2.50Å

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