4a35: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A35 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A35 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a35 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a35 RCSB], [http://www.ebi.ac.uk/pdbsum/4a35 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a35 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a35 RCSB], [http://www.ebi.ac.uk/pdbsum/4a35 PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ENOF1_HUMAN ENOF1_HUMAN]] May regulate thymidylate synthase activity.<ref>PMID:8869746</ref> <ref>PMID:14508106</ref> 
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C.]]
[[Category: Bountra, C]]
[[Category: Canning, P.]]
[[Category: Canning, P]]
[[Category: Delft, F Von.]]
[[Category: Delft, F Von]]
[[Category: Edwards, A M.]]
[[Category: Edwards, A M]]
[[Category: Froese, D S.]]
[[Category: Froese, D S]]
[[Category: Krojer, T.]]
[[Category: Krojer, T]]
[[Category: Muniz, J R.C.]]
[[Category: Muniz, J R.C]]
[[Category: Oppermann, U.]]
[[Category: Oppermann, U]]
[[Category: Vollmar, M.]]
[[Category: Vollmar, M]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Yue, W W.]]
[[Category: Yue, W W]]
[[Category: Isomerase]]
[[Category: Isomerase]]

Revision as of 02:25, 25 December 2014

CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 (ENOSF1)CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 (ENOSF1)

Structural highlights

4a35 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[ENOF1_HUMAN] May regulate thymidylate synthase activity.[1] [2]

References

  1. Dolnick BJ, Black AR, Winkler PM, Schindler K, Hsueh CT. rTS gene expression is associated with altered cell sensitivity to thymidylate synthase inhibitors. Adv Enzyme Regul. 1996;36:165-80. PMID:8869746
  2. Dolnick BJ, Angelino NJ, Dolnick R, Sufrin JR. A novel function for the rTS gene. Cancer Biol Ther. 2003 Jul-Aug;2(4):364-9. PMID:14508106

4a35, resolution 1.74Å

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OCA