3v70: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3v70]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lxw 3lxw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V70 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V70 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3v70]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lxw 3lxw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V70 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V70 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GIMAP1, IMAP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GIMAP1, IMAP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v70 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v70 RCSB], [http://www.ebi.ac.uk/pdbsum/3v70 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v70 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v70 RCSB], [http://www.ebi.ac.uk/pdbsum/3v70 PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/GIMA1_HUMAN GIMA1_HUMAN]] May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Andrews, D W.]]
[[Category: Andrews, D W]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev, A]]
[[Category: Bountra, C.]]
[[Category: Bountra, C]]
[[Category: Edwards, A M.]]
[[Category: Edwards, A M]]
[[Category: Mackenzie, F.]]
[[Category: Mackenzie, F]]
[[Category: Nedyalkova, L.]]
[[Category: Nedyalkova, L]]
[[Category: Park, H.]]
[[Category: Park, H]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Shen, Y.]]
[[Category: Shen, Y]]
[[Category: Tempel, W.]]
[[Category: Tempel, W]]
[[Category: Tong, Y.]]
[[Category: Tong, Y]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Gtpase]]
[[Category: Gtpase]]
[[Category: Immune system]]
[[Category: Immune system]]
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[[Category: Immunity-associated protein]]
[[Category: Immunity-associated protein]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]

Revision as of 22:40, 25 December 2014

Crystal Structure of Human GTPase IMAP family member 1Crystal Structure of Human GTPase IMAP family member 1

Structural highlights

3v70 is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3lxw. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:GIMAP1, IMAP1 (Homo sapiens)
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[GIMA1_HUMAN] May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity).

3v70, resolution 2.21Å

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OCA