3mpc: Difference between revisions
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3mpc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MPC FirstGlance]. <br> | <table><tr><td colspan='2'>[[3mpc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MPC FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cthe_2193 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1515 Clostridium thermocellum])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cthe_2193 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1515 Clostridium thermocellum])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mpc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mpc RCSB], [http://www.ebi.ac.uk/pdbsum/3mpc PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mpc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mpc RCSB], [http://www.ebi.ac.uk/pdbsum/3mpc PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 23: | Line 23: | ||
Structure of a fibronectin type III-like module from Clostridium thermocellum.,Alahuhta M, Xu Q, Brunecky R, Adney WS, Ding SY, Himmel ME, Lunin VV Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Aug 1;66(Pt, 8):878-80. Epub 2010 Jul 27. PMID:20693658<ref>PMID:20693658</ref> | Structure of a fibronectin type III-like module from Clostridium thermocellum.,Alahuhta M, Xu Q, Brunecky R, Adney WS, Ding SY, Himmel ME, Lunin VV Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Aug 1;66(Pt, 8):878-80. Epub 2010 Jul 27. PMID:20693658<ref>PMID:20693658</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
| Line 30: | Line 30: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Clostridium thermocellum]] | [[Category: Clostridium thermocellum]] | ||
[[Category: Alahuhta, M P | [[Category: Alahuhta, M P]] | ||
[[Category: Brunecky, R | [[Category: Brunecky, R]] | ||
[[Category: Lunin, V V | [[Category: Lunin, V V]] | ||
[[Category: Xu, Q | [[Category: Xu, Q]] | ||
[[Category: Fibronectin]] | [[Category: Fibronectin]] | ||
[[Category: Fn3]] | [[Category: Fn3]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Revision as of 22:04, 24 December 2014
The crystal structure of a Fn3-like protein from Clostridium thermocellumThe crystal structure of a Fn3-like protein from Clostridium thermocellum
Structural highlights
Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMedThe 1.6 A resolution structure of a fibronectin type III-like module from Clostridium thermocellum (PDB code 3mpc) with two molecules in the asymmetric unit is reported. The crystals used for data collection belonged to space group P2(1)2(1)2(1), with unit-cell parameters a=35.43, b=45.73, c=107.72 A, and the structure was refined to an R factor of 0.166. Structural comparisons found over 800 similar structures in the Protein Data Bank. The broad range of different proteins or protein domains with high structural similarity makes it especially demanding to classify these proteins. Previous studies of fibronectin type III-like modules have indicated that they might function as ligand-binding modules, as a compact form of peptide linkers or spacers between other domains, as cellulose-disrupting modules or as proteins that help large enzyme complexes remain soluble. Structure of a fibronectin type III-like module from Clostridium thermocellum.,Alahuhta M, Xu Q, Brunecky R, Adney WS, Ding SY, Himmel ME, Lunin VV Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Aug 1;66(Pt, 8):878-80. Epub 2010 Jul 27. PMID:20693658[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
|
| ||||||||||||||||||