2x47: Difference between revisions
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<StructureSection load='2x47' size='340' side='right' caption='[[2x47]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2x47' size='340' side='right' caption='[[2x47]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2x47]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X47 OCA]. <br> | <table><tr><td colspan='2'>[[2x47]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X47 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x47 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x47 RCSB], [http://www.ebi.ac.uk/pdbsum/2x47 PDBsum]</span></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x47 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x47 RCSB], [http://www.ebi.ac.uk/pdbsum/2x47 PDBsum]</span></td></tr> | </table> | ||
<table> | |||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/MACD1_HUMAN MACD1_HUMAN]] A chromosomal aberration involving MACROD1 is found in acute leukemia. Translocation t(11;21)(q13;q22) that forms a RUNX1-MACROD1 fusion protein. | [[http://www.uniprot.org/uniprot/MACD1_HUMAN MACD1_HUMAN]] A chromosomal aberration involving MACROD1 is found in acute leukemia. Translocation t(11;21)(q13;q22) that forms a RUNX1-MACROD1 fusion protein. | ||
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Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases.,Chen D, Vollmar M, Rossi MN, Phillips C, Kraehenbuehl R, Slade D, Mehrotra PV, von Delft F, Crosthwaite SK, Gileadi O, Denu JM, Ahel I J Biol Chem. 2011 Apr 15;286(15):13261-71. Epub 2011 Jan 21. PMID:21257746<ref>PMID:21257746</ref> | Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases.,Chen D, Vollmar M, Rossi MN, Phillips C, Kraehenbuehl R, Slade D, Mehrotra PV, von Delft F, Crosthwaite SK, Gileadi O, Denu JM, Ahel I J Biol Chem. 2011 Apr 15;286(15):13261-71. Epub 2011 Jan 21. PMID:21257746<ref>PMID:21257746</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||