2lf6: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 2: | Line 2: | ||
<StructureSection load='2lf6' size='340' side='right' caption='[[2lf6]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2lf6' size='340' side='right' caption='[[2lf6]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2lf6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._phaseolicola_1448a Pseudomonas syringae pv. phaseolicola 1448a]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LF6 OCA]. <br> | <table><tr><td colspan='2'>[[2lf6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._phaseolicola_1448a Pseudomonas syringae pv. phaseolicola 1448a]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LF6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LF6 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hopAB1, virPphA, PSPPH_A0127 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264730 Pseudomonas syringae pv. phaseolicola 1448A])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hopAB1, virPphA, PSPPH_A0127 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264730 Pseudomonas syringae pv. phaseolicola 1448A])</td></tr> | ||
<tr | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lf6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lf6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lf6 RCSB], [http://www.ebi.ac.uk/pdbsum/2lf6 PDBsum]</span></td></tr> | ||
</table> | |||
<table> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 13: | Line 12: | ||
Structural Analysis of HopPmaL Reveals the Presence of a Second Adaptor Domain Common to the HopAB Family of Pseudomonas syringae Type III Effectors.,Singer AU, Wu B, Yee A, Houliston S, Xu X, Cui H, Skarina T, Garcia M, Semesi A, Arrowsmith CH, Savchenko A Biochemistry. 2012 Jan 10;51(1):1-3. Epub 2011 Dec 28. PMID:22191472<ref>PMID:22191472</ref> | Structural Analysis of HopPmaL Reveals the Presence of a Second Adaptor Domain Common to the HopAB Family of Pseudomonas syringae Type III Effectors.,Singer AU, Wu B, Yee A, Houliston S, Xu X, Cui H, Skarina T, Garcia M, Semesi A, Arrowsmith CH, Savchenko A Biochemistry. 2012 Jan 10;51(1):1-3. Epub 2011 Dec 28. PMID:22191472<ref>PMID:22191472</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
| Line 20: | Line 19: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Pseudomonas syringae pv. phaseolicola 1448a]] | [[Category: Pseudomonas syringae pv. phaseolicola 1448a]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Garcia, M | [[Category: Garcia, M]] | ||
[[Category: Houliston, S | [[Category: Houliston, S]] | ||
[[Category: Joachimiak, A | [[Category: Joachimiak, A]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Montelione, G T | [[Category: Montelione, G T]] | ||
[[Category: OCSP, Ontario Centre for Structural Proteomics]] | |||
[[Category: OCSP, Ontario Centre for Structural Proteomics | [[Category: Savchenko, A]] | ||
[[Category: Savchenko, A | [[Category: Semesi, A]] | ||
[[Category: Semesi, A | [[Category: Singer, A U]] | ||
[[Category: Singer, A U | [[Category: Wu, B]] | ||
[[Category: Wu, B | [[Category: Yee, A]] | ||
[[Category: Yee, A | |||
[[Category: Mcsg]] | [[Category: Mcsg]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
[[Category: Ocsp]] | [[Category: Ocsp]] | ||
[[Category: Ontario centre for structural proteomic]] | [[Category: Ontario centre for structural proteomic]] | ||
[[Category: Protein structure initiative]] | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
[[Category: Type iii effector]] | [[Category: Type iii effector]] | ||
Revision as of 08:47, 22 December 2014
Solution NMR structure of HopABPph1448_220_320 from Pseudomonas syringae pv. phaseolicola str. 1448A, Midwest Center for Structural Genomics target APC40132.4 and Northeast Structural Genomics Consortium target PsT3ASolution NMR structure of HopABPph1448_220_320 from Pseudomonas syringae pv. phaseolicola str. 1448A, Midwest Center for Structural Genomics target APC40132.4 and Northeast Structural Genomics Consortium target PsT3A
Structural highlights
Publication Abstract from PubMedHopPmaL is a member of the HopAB family of type III effectors present in the phytopathogen Pseudomonas syringae. Using both X-ray crystallography and solution nuclear magnetic resonance, we demonstrate that HopPmaL contains two structurally homologous yet functionally distinct domains. The N-terminal domain corresponds to the previously described Pto-binding domain, while the previously uncharacterised C-terminal domain spans residues 308-385. While structurally similar, these domains do not share significant sequence similarity and most importantly demonstrate significant differences in key residues involved in host protein recognition, suggesting that each of them targets a different host protein. Structural Analysis of HopPmaL Reveals the Presence of a Second Adaptor Domain Common to the HopAB Family of Pseudomonas syringae Type III Effectors.,Singer AU, Wu B, Yee A, Houliston S, Xu X, Cui H, Skarina T, Garcia M, Semesi A, Arrowsmith CH, Savchenko A Biochemistry. 2012 Jan 10;51(1):1-3. Epub 2011 Dec 28. PMID:22191472[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
|
| ||||||||||||||||
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pseudomonas syringae pv. phaseolicola 1448a
- Arrowsmith, C H
- Garcia, M
- Houliston, S
- Joachimiak, A
- Structural genomic
- Montelione, G T
- OCSP, Ontario Centre for Structural Proteomics
- Savchenko, A
- Semesi, A
- Singer, A U
- Wu, B
- Yee, A
- Mcsg
- Nesg
- Ocsp
- Ontario centre for structural proteomic
- PSI, Protein structure initiative
- Psi-biology
- Signaling protein
- Type iii effector