2q63: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2q63.jpg|left|200px]]<br /><applet load="2q63" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2q63.jpg|left|200px]]
-caption="2q63, resolution 2.20&Aring;" />
-'''HIV-1 PR mutant in complex with nelfinavir'''<br />
+ {{Structure
+|PDB= 2q63 |SIZE=350|CAPTION= <scene name='initialview01'>2q63</scene>, resolution 2.20&Aring;
+|SITE= <scene name='pdbsite=AC1:1un+Binding+Site+For+Residue+A+1001'>AC1</scene>
+|LIGAND= <scene name='pdbligand=1UN:2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE'>1UN</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
+|GENE= gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
+}}
+'''HIV-1 PR mutant in complex with nelfinavir'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-Q63 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=1UN:'>1UN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Known structural/functional Site: <scene name='pdbsite=AC1:1un+Binding+Site+For+Residue+A+1001'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q63 OCA].
+Q63 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q63 OCA].
 ==Reference==
-Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants., Kozisek M, Bray J, Rezacova P, Saskova K, Brynda J, Pokorna J, Mammano F, Rulisek L, Konvalinka J, J Mol Biol. 2007 Dec 7;374(4):1005-16. Epub 2007 Oct 3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17977555 17977555]
+Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants., Kozisek M, Bray J, Rezacova P, Saskova K, Brynda J, Pokorna J, Mammano F, Rulisek L, Konvalinka J, J Mol Biol. 2007 Dec 7;374(4):1005-16. Epub 2007 Oct 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17977555 17977555]
 [[Category: HIV-1 retropepsin]]
 [[Category: Human immunodeficiency virus 1]]
@@ Line 24: / Line 33: @@
 [[Category: resistance]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  5 13:25:40 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:22:07 2008''