Protein phosphatase: Difference between revisions

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-[[Image:3k7v.png|left|200px|thumb|Crystal structure of human PP2A catalytic (pink) and regulatory (grey) subunits complex with tumor-inducing toxin binding protein  [[3k7v]]]]
 {{STRUCTURE_3k7v|  PDB=3k7v  | SIZE=400| SCENE= |right|CAPTION=Human PP2A catalytic (pink) and regulatory (grey) subunits complex with tumor-inducing toxin and sulfate [[3k7v]] }}
 '''Protein phosphatases''' (PP) regular protein phosphorylation and thus are key in intracellular signal transduction processes.   PP1 is a serine/threonine phosphatase.  PP2A targets proteins in the oncogenic signaling pathways.  PP2C are Mg/Mn- dependent and are essential for the regulation of cell cycle and stress signaling pathways.  PP4 regulates a variety of cellular functions.  PP5 is activated by lipids and is involved in signal transduction.  For PP2A see also [[HEAT Repeat]].