Sandbox reserved 915: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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 MGL degrades [http://en.wikipedia.org/wiki/2-Arachidonoylglycerol 2-Arachidonoylglycerol 2-AG]. 2-AG is commonly classified as an [http://books.google.com/booksid=BxfLB4n3uoMC&pg=PA34&lpg=PA34&dq=hydrolysis+of+2-AG+by+MGL&source=bl&ots=R6Xm0KgGdK&sig=K3AwwtDNxbNUKJoa3zsd_25wVKs&hl=en&sa=X&ei=yOI5U43kCcbUsAT9_4DoBw&ved=0CGEQ6AEwCg#v=onepage&q=hydrolysis%20of%202-AG%20by%20MGL&f=false Endocannabinoid]
 .  In the brain endocannabinoids are released from postsynaptic neurons, causing the retrograde suppression of synaptic transmission.
-In Peripheral tissues,  EC is active in autonomic nervous system.  EC affects processes such as learning, motor control, cognition, and pain. EC is also able to regulate lipid metabolism and food intake.
+In Peripheral tissues,  EC is active in autonomic nervous system.  EC affects processes such as learning, motor control, cognition, and pain. EC is also able to regulate lipid metabolism and food intake. Looking at the role of MGL in energy metabolism, a deficiency in MGL in animals led to the buildup of 2-AG <ref name="Taschler" />.
- Looking at the role of MGL in energy metabolism, a defiency in MGL in animals led to the buildup of 2-AG <ref name="Taschler" />.
 ===Inhibition of MGL===