6fit: Difference between revisions

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[[Image:6fit.jpg|left|200px]]<br /><applet load="6fit" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:6fit.jpg|left|200px]]
caption="6fit, resolution 2.6&Aring;" />
 
'''FHIT-TRANSITION STATE ANALOG'''<br />
{{Structure
|PDB= 6fit |SIZE=350|CAPTION= <scene name='initialview01'>6fit</scene>, resolution 2.6&Aring;
|SITE= <scene name='pdbsite=AVE:Active+Site+HIS+Responsible+For+Forming+The+Transient+Nu+...'>AVE</scene> and <scene name='pdbsite=HNE:HIS+Triad+For+Which+This+Family+Was+Named'>HNE</scene>
|LIGAND= <scene name='pdbligand=AMW:ADENOSINE MONOTUNGSTATE'>AMW</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Bis(5'-adenosyl)-triphosphatase Bis(5'-adenosyl)-triphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.29 3.6.1.29]
|GENE= FHIT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''FHIT-TRANSITION STATE ANALOG'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
6FIT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=AMW:'>AMW</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Bis(5'-adenosyl)-triphosphatase Bis(5'-adenosyl)-triphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.29 3.6.1.29] Known structural/functional Sites: <scene name='pdbsite=AVE:Active+Site+HIS+Responsible+For+Forming+The+Transient+Nu+...'>AVE</scene> and <scene name='pdbsite=HNE:HIS+Triad+For+Which+This+Family+Was+Named'>HNE</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FIT OCA].  
6FIT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FIT OCA].  


==Reference==
==Reference==
Structure-based analysis of catalysis and substrate definition in the HIT protein family., Lima CD, Klein MG, Hendrickson WA, Science. 1997 Oct 10;278(5336):286-90. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9323207 9323207]
Structure-based analysis of catalysis and substrate definition in the HIT protein family., Lima CD, Klein MG, Hendrickson WA, Science. 1997 Oct 10;278(5336):286-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9323207 9323207]
[[Category: Bis(5'-adenosyl)-triphosphatase]]
[[Category: Bis(5'-adenosyl)-triphosphatase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: putative tumor suppressor]]
[[Category: putative tumor suppressor]]


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