4nd6: Difference between revisions

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{{STRUCTURE_4nd6|  PDB=4nd6  |  SCENE=  }}  
{{STRUCTURE_4nd6|  PDB=4nd6  |  SCENE=  }}  
===Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open form===
===Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open form===
{{ABSTRACT_PUBMED_24611875}}


==Function==
==Function==
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==About this Structure==
==About this Structure==
[[4nd6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ND6 OCA].  
[[4nd6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ND6 OCA].  


==Reference==
==Reference==
<references group="xtra"/><references/>
<ref group="xtra">PMID:024611875</ref><references group="xtra"/><references/>
[[Category: Metja]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Cooley, R B.]]
[[Category: Cooley, R B.]]

Revision as of 10:36, 16 April 2014

Template:STRUCTURE 4nd6

Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open formCrystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open form

Template:ABSTRACT PUBMED 24611875

FunctionFunction

[SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[1]

About this StructureAbout this Structure

4nd6 is a 1 chain structure with sequence from Metja. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Cooley RB, Feldman JL, Driggers CM, Bundy TA, Stokes AL, Karplus PA, Mehl RA. Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases. Biochemistry. 2014 Apr 1;53(12):1916-24. doi: 10.1021/bi5001239. Epub 2014 Mar, 20. PMID:24611875 doi:http://dx.doi.org/10.1021/bi5001239
  1. Steer BA, Schimmel P. Major anticodon-binding region missing from an archaebacterial tRNA synthetase. J Biol Chem. 1999 Dec 10;274(50):35601-6. PMID:10585437

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