4ps5: Difference between revisions

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OCA

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-'''Unreleased structure'''
+{{STRUCTURE_4ps5|  PDB=4ps5  |  SCENE=  }}
+===Crystal structure of the first bromodomain of human BRD4 in complex with TG101348===
+{{ABSTRACT_PUBMED_24568369}}
-The entry 4ps5 is ON HOLD
+==Disease==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
-Authors: Ember, S.W., Zhu, J.-Y., Watts, C., Schonbrunn, E.
+==Function==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
-Description: CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH TG101348
+==About this Structure==
+[[4ps5]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4o73 4o73]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PS5 OCA].
+==Reference==
+<ref group="xtra">PMID:024568369</ref><references group="xtra"/><references/>
+[[Category: Ember, S W.]]
+[[Category: Schonbrunn, E.]]
+[[Category: Watts, C.]]
+[[Category: Zhu, J Y.]]
+[[Category: Bromodomain]]
+[[Category: Cap]]
+[[Category: Cell cycle]]
+[[Category: Hunk1]]
+[[Category: Inhibitor]]
+[[Category: Mcap]]
+[[Category: Mitotic chromosome associated protein]]
+[[Category: Protein binding-inhibitor complex]]
+[[Category: Transcription-inhibitor complex]]
+[[Category: Transcription-transcription inhibitor complex]]