4ot8: Difference between revisions

m Protected "4ot8" [edit=sysop:move=sysop]
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'''Unreleased structure'''
{{STRUCTURE_4ot8|  PDB=4ot8  |  SCENE=  }}
===X-ray Crystal Structure of Serine Hydroxymethyl Transferase from Burkholderia cenocepacia bound to PLP and Serine===


The entry 4ot8 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/B4ECY9_BURCJ B4ECY9_BURCJ]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051]


Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
==About this Structure==
 
[[4ot8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OT8 OCA].
Description: X-ray Crystal Structure of Serine Hydroxymethyl Transferase from Burkholderia cenocepacia bound to PLP and Serine
[[Category: Glycine hydroxymethyltransferase]]
[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Seattle structural genomics center for infectious disease]]
[[Category: Serine hydroxymethyl transferase]]
[[Category: Ssgcid]]
[[Category: Structural genomic]]
[[Category: Transferase]]

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