3c0z: Difference between revisions

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New page: left|200px<br /><applet load="3c0z" size="350" color="white" frame="true" align="right" spinBox="true" caption="3c0z, resolution 2.10Å" /> '''Crystal structure of...
 
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[[Image:3c0z.jpg|left|200px]]<br /><applet load="3c0z" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3c0z.jpg|left|200px]]
caption="3c0z, resolution 2.10&Aring;" />
 
'''Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with SAHA'''<br />
{{Structure
|PDB= 3c0z |SIZE=350|CAPTION= <scene name='initialview01'>3c0z</scene>, resolution 2.10&Aring;
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+101'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+102'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+B+101'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+B+102'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+C+101'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+C+102'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Residue+A+201'>AC7</scene>, <scene name='pdbsite=AC8:K+Binding+Site+For+Residue+A+202'>AC8</scene>, <scene name='pdbsite=AC9:K+Binding+Site+For+Residue+B+201'>AC9</scene>, <scene name='pdbsite=BC1:K+Binding+Site+For+Residue+B+202'>BC1</scene>, <scene name='pdbsite=BC2:K+Binding+Site+For+Residue+C+201'>BC2</scene>, <scene name='pdbsite=BC3:K+Binding+Site+For+Residue+C+202'>BC3</scene>, <scene name='pdbsite=BC4:Shh+Binding+Site+For+Residue+A+301'>BC4</scene>, <scene name='pdbsite=BC5:Shh+Binding+Site+For+Residue+B+301'>BC5</scene> and <scene name='pdbsite=BC6:Shh+Binding+Site+For+Residue+C+301'>BC6</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> and <scene name='pdbligand=SHH:OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE'>SHH</scene>
|ACTIVITY=
|GENE= HDAC7A, HDAC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with SAHA'''
 


==About this Structure==
==About this Structure==
3C0Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=SHH:'>SHH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2PQO. Known structural/functional Sites: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+101'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+102'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+B+101'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+B+102'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+C+101'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+C+102'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Residue+A+201'>AC7</scene>, <scene name='pdbsite=AC8:K+Binding+Site+For+Residue+A+202'>AC8</scene>, <scene name='pdbsite=AC9:K+Binding+Site+For+Residue+B+201'>AC9</scene>, <scene name='pdbsite=BC1:K+Binding+Site+For+Residue+B+202'>BC1</scene>, <scene name='pdbsite=BC2:K+Binding+Site+For+Residue+C+201'>BC2</scene>, <scene name='pdbsite=BC3:K+Binding+Site+For+Residue+C+202'>BC3</scene>, <scene name='pdbsite=BC4:Shh+Binding+Site+For+Residue+A+301'>BC4</scene>, <scene name='pdbsite=BC5:Shh+Binding+Site+For+Residue+B+301'>BC5</scene> and <scene name='pdbsite=BC6:Shh+Binding+Site+For+Residue+C+301'>BC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C0Z OCA].  
3C0Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2PQO. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C0Z OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 30: Line 39:
[[Category: repressor]]
[[Category: repressor]]
[[Category: sgc]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: transcription]]
[[Category: transcription]]
[[Category: transcription regulation]]
[[Category: transcription regulation]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:08:06 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:02:04 2008''

Revision as of 20:02, 20 March 2008

File:3c0z.jpg


PDB ID 3c0z

Drag the structure with the mouse to rotate
, resolution 2.10Å
Sites: , , , , , , , , , , , , , and
Ligands: , and
Gene: HDAC7A, HDAC7 (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with SAHA


About this StructureAbout this Structure

3C0Z is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2PQO. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 19:02:04 2008

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