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{{STRUCTURE_3wql| PDB=3wql | SCENE= }} | |||
===Crystal structure of Rv3378c with Mg2+ and PPi=== | |||
{{ABSTRACT_PUBMED_24475925}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TUBOL_MYCTU TUBOL_MYCTU]] Catalyzes the PP-removal from tuberculosinyl diphosphate to produce both tubercilosinol and isotuberculosinol. Can also use labdadienyl diphosphates, copalyl diphosphate (CDP), ent-CDP and syn-CDP in vitro. | |||
==About this Structure== | |||
[[3wql]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WQL OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024475925</ref><references group="xtra"/><references/> | |||
[[Category: Bogue, S.]] | |||
[[Category: Chan, H C.]] | |||
[[Category: Crick, D C.]] | |||
[[Category: Feng, X.]] | |||
[[Category: Guo, R T.]] | |||
[[Category: Hoshino, T.]] | |||
[[Category: Hu, Y.]] | |||
[[Category: Huang, C H.]] | |||
[[Category: Ko, T P.]] | |||
[[Category: Liang, P H.]] | |||
[[Category: Liu, W.]] | |||
[[Category: Lv, P.]] | |||
[[Category: Nakano, C.]] | |||
[[Category: Oldfield, E.]] | |||
[[Category: Wang, A H.]] | |||
[[Category: Zhang, L.]] | |||
[[Category: Zheng, Y.]] | |||
[[Category: Diterpene synthase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Phosphatase]] | |||
Revision as of 20:19, 19 February 2014
Crystal structure of Rv3378c with Mg2+ and PPiCrystal structure of Rv3378c with Mg2+ and PPi
Template:ABSTRACT PUBMED 24475925
FunctionFunction
[TUBOL_MYCTU] Catalyzes the PP-removal from tuberculosinyl diphosphate to produce both tubercilosinol and isotuberculosinol. Can also use labdadienyl diphosphates, copalyl diphosphate (CDP), ent-CDP and syn-CDP in vitro.
About this StructureAbout this Structure
3wql is a 4 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Chan HC, Feng X, Ko TP, Huang CH, Hu Y, Zheng Y, Bogue S, Nakano C, Hoshino T, Zhang L, Lv P, Liu W, Crick DC, Liang PH, Wang AH, Oldfield E, Guo RT. Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis. J Am Chem Soc. 2014 Feb 5. PMID:24475925 doi:http://dx.doi.org/10.1021/ja413127v