3kko: Difference between revisions
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Revision as of 06:23, 13 February 2014
Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHpCrystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp
Template:ABSTRACT PUBMED 20479006
FunctionFunction
[RASM_MOUSE] May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway (By similarity).
About this StructureAbout this Structure
3kko is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Shima F, Ijiri Y, Muraoka S, Liao J, Ye M, Araki M, Matsumoto K, Yamamoto N, Sugimoto T, Yoshikawa Y, Kumasaka T, Yamamoto M, Tamura A, Kataoka T. Structural basis for conformational dynamics of GTP-bound Ras protein. J Biol Chem. 2010 Jul 16;285(29):22696-705. Epub 2010 May 17. PMID:20479006 doi:10.1074/jbc.M110.125161