3b7o: Difference between revisions
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[[Image:3b7o.gif|left|200px]] | [[Image:3b7o.gif|left|200px]] | ||
'''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site''' | {{Structure | ||
|PDB= 3b7o |SIZE=350|CAPTION= <scene name='initialview01'>3b7o</scene>, resolution 1.60Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=MLT:MALATE ION'>MLT</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] | |||
|GENE= PTPN11, PTP2C, SHPTP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site''' | |||
==Disease== | ==Disease== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
3B7O is a [ | 3B7O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7O OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
| Line 38: | Line 47: | ||
[[Category: sh2 domain]] | [[Category: sh2 domain]] | ||
[[Category: shp2]] | [[Category: shp2]] | ||
[[Category: structural | [[Category: structural genomic]] | ||
[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
[[Category: tyrosine phosphatase]] | [[Category: tyrosine phosphatase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:56:49 2008'' | ||
Revision as of 19:56, 20 March 2008
| |||||||
| , resolution 1.60Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | PTPN11, PTP2C, SHPTP2 (Homo sapiens) | ||||||
| Activity: | Protein-tyrosine-phosphatase, with EC number 3.1.3.48 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site
DiseaseDisease
Known diseases associated with this structure: Leopard syndrome OMIM:[176876], Leukemia, juvenile myelomonocytic OMIM:[176876], Noonan syndrome 1 OMIM:[176876]
About this StructureAbout this Structure
3B7O is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:56:49 2008
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- Protein-tyrosine-phosphatase
- Single protein
- Arrowsmith, C H.
- Barr, A.
- Delft, F von.
- Edwards, A M.
- Elkins, J.
- King, O.
- Knapp, S.
- Niesen, F.
- Patel, A.
- Pilka, E S.
- SGC, Structural Genomics Consortium.
- Salah, E.
- Savitsky, P.
- Ugochukwu, E.
- Weigelt, J.
- MLT
- Alternative splicing
- Cytoplasm
- Deafness
- Disease mutation
- Hydrolase
- Phosphorylation
- Protein phosphatase
- Ptpn11
- Sgc
- Sh2 domain
- Shp2
- Structural genomic
- Structural genomics consortium
- Tyrosine phosphatase