2z3c: Difference between revisions
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[[Image:2z3c.gif|left|200px]] | [[Image:2z3c.gif|left|200px]] | ||
'''A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase''' | {{Structure | ||
|PDB= 2z3c |SIZE=350|CAPTION= <scene name='initialview01'>2z3c</scene>, resolution 1.79Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=MBN:TOLUENE'>MBN</scene>, <scene name='pdbligand=KCQ:(3S)-3-[(2S)-2-AMINO-3-OXOBUTYL]PYRROLIDIN-2-ONE'>KCQ</scene>, <scene name='pdbligand=ECQ:(3S)-3-[(2S)-2-AMINO-3-HYDROXYBUTYL]PYRROLIDIN-2-ONE'>ECQ</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | |||
|ACTIVITY= | |||
|GENE= rep ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=227859 SARS coronavirus]) | |||
}} | |||
'''A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2Z3C is a [ | 2Z3C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z3C OCA]. | ||
==Reference== | ==Reference== | ||
A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase., Yin J, Niu C, Cherney MM, Zhang J, Huitema C, Eltis LD, Vederas JC, James MN, J Mol Biol. 2007 Aug 24;371(4):1060-74. Epub 2007 Jun 8. PMID:[http:// | A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase., Yin J, Niu C, Cherney MM, Zhang J, Huitema C, Eltis LD, Vederas JC, James MN, J Mol Biol. 2007 Aug 24;371(4):1060-74. Epub 2007 Jun 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17599357 17599357] | ||
[[Category: Sars coronavirus]] | [[Category: Sars coronavirus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: KCQ]] | [[Category: KCQ]] | ||
[[Category: MBN]] | [[Category: MBN]] | ||
[[Category: beta | [[Category: beta barrel]] | ||
[[Category: hydrolase]] | [[Category: hydrolase]] | ||
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