2z3c: Difference between revisions

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[[Image:2z3c.gif|left|200px]]<br /><applet load="2z3c" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2z3c.gif|left|200px]]
caption="2z3c, resolution 1.79&Aring;" />
 
'''A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase'''<br />
{{Structure
|PDB= 2z3c |SIZE=350|CAPTION= <scene name='initialview01'>2z3c</scene>, resolution 1.79&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MBN:TOLUENE'>MBN</scene>, <scene name='pdbligand=KCQ:(3S)-3-[(2S)-2-AMINO-3-OXOBUTYL]PYRROLIDIN-2-ONE'>KCQ</scene>, <scene name='pdbligand=ECQ:(3S)-3-[(2S)-2-AMINO-3-HYDROXYBUTYL]PYRROLIDIN-2-ONE'>ECQ</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE= rep ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=227859 SARS coronavirus])
}}
 
'''A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Z3C is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus] with <scene name='pdbligand=MBN:'>MBN</scene>, <scene name='pdbligand=KCQ:'>KCQ</scene>, <scene name='pdbligand=ECQ:'>ECQ</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z3C OCA].  
2Z3C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z3C OCA].  


==Reference==
==Reference==
A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase., Yin J, Niu C, Cherney MM, Zhang J, Huitema C, Eltis LD, Vederas JC, James MN, J Mol Biol. 2007 Aug 24;371(4):1060-74. Epub 2007 Jun 8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17599357 17599357]
A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase., Yin J, Niu C, Cherney MM, Zhang J, Huitema C, Eltis LD, Vederas JC, James MN, J Mol Biol. 2007 Aug 24;371(4):1060-74. Epub 2007 Jun 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17599357 17599357]
[[Category: Sars coronavirus]]
[[Category: Sars coronavirus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: KCQ]]
[[Category: KCQ]]
[[Category: MBN]]
[[Category: MBN]]
[[Category: beta barrels]]
[[Category: beta barrel]]
[[Category: hydrolase]]
[[Category: hydrolase]]


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