Introduction to protein structure: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Ann Taylor, Israel Hanukoglu, Jaime Prilusky, Joel L. Sussman, Nick Kenworthy, Alexander Berchansky, Eric Martz

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 This tutorial illustrates some basic properties of protein structure and useful commands in Jmol and Proteopedia.  Clicking the green links changes the view in the structure box to illustrate the principle described by the text.  If the structure box has a puzzle piece in it, please make sure you have the latest version of [[Java]] installed and follow the directions to allow Proteopedia to run.
-Proteins are condensation polymers of amino acids.  The <scene name='57/575866/Primary_sequence/1'>primary structure</scene> is the amino acid sequence.  The <scene name='57/575866/Secondary_sequence/1'>secondary structure</scene> is the local structure over short distances.  This level of structure is stabilized by <scene name='57/575866/H_bond_a_helix/1'>hydrogen bonds</scene> along the <scene name='57/575866/Backbone/1'>backbone</scene>.  These secondary structures <scene name='57/575866/Global_secondary_structures/1'>pack together</scene> to form the overall form of the entire peptide chain, called the <scene name='57/575866/Tertiary/1'>tertiary structure</scene>.  Some proteins, such as the displayed hemoglobin molecule, have more than one polypeptide chain that associate to form the functional unit of the protein; this is called <scene name='57/575866/Tertiary/2'>quaternary structure</scene>.
+Proteins are condensation polymers of amino acids.  The <scene name='57/575866/Primary_sequence/2'>primary structure</scene> is the amino acid sequence.  The <scene name='57/575866/Secondary_sequence/1'>secondary structure</scene> is the local structure over short distances.  This level of structure is stabilized by <scene name='57/575866/H_bond_a_helix/1'>hydrogen bonds</scene> along the <scene name='57/575866/Backbone/1'>backbone</scene>.  These secondary structures <scene name='57/575866/Global_secondary_structures/1'>pack together</scene> to form the overall form of the entire peptide chain, called the <scene name='57/575866/Tertiary/1'>tertiary structure</scene>.  Some proteins, such as the displayed hemoglobin molecule, have more than one polypeptide chain that associate to form the functional unit of the protein; this is called <scene name='57/575866/Tertiary/2'>quaternary structure</scene>.
 '''Questions based upon these scenes:'''