1xek: Difference between revisions
New page: left|200px<br /> <applet load="1xek" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xek, resolution 2.3Å" /> '''THE CRYSTAL STRUCTUR... |
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==About this Structure== | ==About this Structure== | ||
1XEK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1XEK OCA]]. | 1XEK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]]. Active as [[http://en.wikipedia.org/wiki/Hydrolase Hydrolase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]]. Structure known Active Site: CAT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1XEK OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: o-glycosyl]] | [[Category: o-glycosyl]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:42:57 2007'' | ||
Revision as of 09:38, 30 October 2007
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THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION
OverviewOverview
Earlier studies involving water-mediated transformations in lysozyme and, ribonuclease A have shown that the overall movements in the protein, molecule consequent to the reduction in the amount of surrounding water, are similar to those that occur during enzyme action, thus highlighting, the relationship among hydration, plasticity, and action of these enzymes., Monoclinic lysozyme retains its crystallinity even when the level of, hydration is reduced further below that necessary for activity (about 0.2, gram of water per gram of protein). In order to gain insights into the, role of water in the stability and the plasticity of the protein molecule, and the geometrical basis for the loss of activity that accompanies, dehydration, the crystal structures of monoclinic lysozyme with solvent, ... [(full description)]
About this StructureAbout this Structure
1XEK is a [Single protein] structure of sequence from [[1]]. Active as [Hydrolase], with EC number [3.2.1.17]. Structure known Active Site: CAT. Full crystallographic information is available from [OCA].
ReferenceReference
Role of water in plasticity, stability, and action of proteins: the crystal structures of lysozyme at very low levels of hydration., Nagendra HG, Sukumar N, Vijayan M, Proteins. 1998 Aug 1;32(2):229-40. PMID:9714162
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