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= Repercussion of the M129/V129 polymorphism =
= Repercussion of the M129/V129 polymorphism =


[[Image:Images.jpg|left|400px||thumb|'''Polymorphism of β-sheet interface''']]
[[Image:Images.jpg|left|700px||thumb|'''Polymorphism of β-sheet interface''']]


It’s known that the transformation of the normal protein in its infectious model involves a conversion from a soluble and predominantly α-helical protein to an aggregated form, which is substantially enriched in β-sheet.
It’s known that the transformation of the normal protein in its infectious model involves a conversion from a soluble and predominantly α-helical protein to an aggregated form, which is substantially enriched in β-sheet.

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OCA, Pierre-Yves Mocaer