2vc4: Difference between revisions

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[[Image:2vc4.gif|left|200px]]<br /><applet load="2vc4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2vc4.gif|left|200px]]
caption="2vc4, resolution 1.39&Aring;" />
 
'''RICIN A-CHAIN (RECOMBINANT) E177D MUTANT'''<br />
{{Structure
|PDB= 2vc4 |SIZE=350|CAPTION= <scene name='initialview01'>2vc4</scene>, resolution 1.39&Aring;
|SITE= <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Chain+A'>AC2</scene> and <scene name='pdbsite=AC3:So4+Binding+Site+For+Chain+A'>AC3</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22]
|GENE=
}}
 
'''RICIN A-CHAIN (RECOMBINANT) E177D MUTANT'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2VC4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] Known structural/functional Sites: <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Chain+A'>AC2</scene> and <scene name='pdbsite=AC3:So4+Binding+Site+For+Chain+A'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VC4 OCA].  
2VC4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VC4 OCA].  


==Reference==
==Reference==
The isolation and characterization of temperature-dependent ricin A chain molecules in Saccharomyces cerevisiae., Allen SC, Moore KA, Marsden CJ, Fulop V, Moffat KG, Lord JM, Ladds G, Roberts LM, FEBS J. 2007 Nov;274(21):5586-99. Epub 2007 Oct 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17916187 17916187]
The isolation and characterization of temperature-dependent ricin A chain molecules in Saccharomyces cerevisiae., Allen SC, Moore KA, Marsden CJ, Fulop V, Moffat KG, Lord JM, Ladds G, Roberts LM, FEBS J. 2007 Nov;274(21):5586-99. Epub 2007 Oct 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17916187 17916187]
[[Category: Ricinus communis]]
[[Category: Ricinus communis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: toxin]]
[[Category: toxin]]


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