2v1y: Difference between revisions

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[[Image:2v1y.gif|left|200px]]<br /><applet load="2v1y" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2v1y.gif|left|200px]]
caption="2v1y, resolution 2.40&Aring;" />
 
'''STRUCTURE OF A PHOSPHOINOSITIDE 3-KINASE ALPHA ADAPTOR-BINDING DOMAIN (ABD) IN A COMPLEX WITH THE ISH2 DOMAIN FROM P85 ALPHA'''<br />
{{Structure
|PDB= 2v1y |SIZE=350|CAPTION= <scene name='initialview01'>2v1y</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153]
|GENE=
}}
 
'''STRUCTURE OF A PHOSPHOINOSITIDE 3-KINASE ALPHA ADAPTOR-BINDING DOMAIN (ABD) IN A COMPLEX WITH THE ISH2 DOMAIN FROM P85 ALPHA'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2V1Y is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V1Y OCA].  
2V1Y is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V1Y OCA].  


==Reference==
==Reference==
Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit., Miled N, Yan Y, Hon WC, Perisic O, Zvelebil M, Inbar Y, Schneidman-Duhovny D, Wolfson HJ, Backer JM, Williams RL, Science. 2007 Jul 13;317(5835):239-42. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17626883 17626883]
Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit., Miled N, Yan Y, Hon WC, Perisic O, Zvelebil M, Inbar Y, Schneidman-Duhovny D, Wolfson HJ, Backer JM, Williams RL, Science. 2007 Jul 13;317(5835):239-42. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17626883 17626883]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: host-virus interaction]]
[[Category: host-virus interaction]]
[[Category: kinase]]
[[Category: kinase]]
[[Category: oncogenic mutations]]
[[Category: oncogenic mutation]]
[[Category: phosphoinositide]]
[[Category: phosphoinositide]]
[[Category: phosphoinositide 3-kinase]]
[[Category: phosphoinositide 3-kinase]]
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[[Category: ubl conjugation]]
[[Category: ubl conjugation]]


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