2v00: Difference between revisions

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OCA

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-[[Image:2v00.jpg|left|200px]]<br /><applet load="2v00" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2v00.jpg|left|200px]]
-caption="2v00, resolution 1.55&Aring;" />
-'''X-RAY CRYSTAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH COMPOUND 1'''<br />
+ {{Structure
+|PDB= 2v00 |SIZE=350|CAPTION= <scene name='initialview01'>2v00</scene>, resolution 1.55&Aring;
+|SITE= <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Gol+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:Gol+Binding+Site+For+Chain+A'>AC3</scene>, <scene name='pdbsite=AC4:Act+Binding+Site+For+Chain+A'>AC4</scene>, <scene name='pdbsite=AC5:Act+Binding+Site+For+Chain+A'>AC5</scene> and <scene name='pdbsite=AC6:V15+Binding+Site+For+Chain+A'>AC6</scene>
+|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=V15:'>V15</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22]
+|GENE=
+}}
+'''X-RAY CRYSTAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH COMPOUND 1'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-V00 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica] with <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=V15:'>V15</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] Known structural/functional Sites: <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Gol+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:Gol+Binding+Site+For+Chain+A'>AC3</scene>, <scene name='pdbsite=AC4:Act+Binding+Site+For+Chain+A'>AC4</scene>, <scene name='pdbsite=AC5:Act+Binding+Site+For+Chain+A'>AC5</scene> and <scene name='pdbsite=AC6:V15+Binding+Site+For+Chain+A'>AC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V00 OCA].
+V00 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V00 OCA].
 ==Reference==
-Discovery of a novel warhead against beta-secretase through fragment-based lead generation., Geschwindner S, Olsson LL, Albert JS, Deinum J, Edwards PD, de Beer T, Folmer RH, J Med Chem. 2007 Nov 29;50(24):5903-11. Epub 2007 Nov 7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17985861 17985861]
+Discovery of a novel warhead against beta-secretase through fragment-based lead generation., Geschwindner S, Olsson LL, Albert JS, Deinum J, Edwards PD, de Beer T, Folmer RH, J Med Chem. 2007 Nov 29;50(24):5903-11. Epub 2007 Nov 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17985861 17985861]
 [[Category: Cryphonectria parasitica]]
 [[Category: Endothiapepsin]]
@@ Line 37: / Line 46: @@
 [[Category: zymogen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:51:59 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:41:46 2008''