4c9x: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4c9x|  PDB=4c9x  |  SCENE=  }}
+===Crystal structure of NUDT1 (MTH1) with S-crizotinib===
-The entry 4c9x is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/8ODP_HUMAN 8ODP_HUMAN]] Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP.<ref>PMID:10373420</ref> <ref>PMID:10608900</ref> <ref>PMID:11139615</ref> <ref>PMID:12857738</ref> <ref>PMID:22556419</ref>
-Authors: Elkins, J.M., Salah, E., Huber, K., Superti-Furga, G., Abdul Azeez, K.R., Krojer, T., Von Delft, F., Bountra, C., Edwards, A., Knapp, S.
+==About this Structure==
+[[4c9x]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C9X OCA].
-Description: Crystal structure of NUDT1 (MTH1) with S-crizotinib
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Azeez, K R.Abdul.]]
+[[Category: Bountra, C.]]
+[[Category: Delft, F Von.]]
+[[Category: Edwards, A.]]
+[[Category: Elkins, J M.]]
+[[Category: Huber, K.]]
+[[Category: Knapp, S.]]
+[[Category: Krojer, T.]]
+[[Category: Salah, E.]]
+[[Category: Superti-Furga, G.]]
+[[Category: Crizotinib]]
+[[Category: Hydrolase]]