Chengfeng Ren/Sandbox1: Difference between revisions
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The IFNβreceptor is composed of 2 required chains—a signaling | The IFNβreceptor is composed of 2 required chains—a signaling | ||
chain, IFNAR1, and a binding chain, IFNAR2. Both IFNAR1 and | chain, IFNAR1, and a binding chain, IFNAR2. Both IFNAR1 and | ||
IFNAR2 are constitutively expressed on the surface of virtually all cells. IFNβcan bind to IFNAR2 alone, but can bind to | IFNAR2 are constitutively expressed on the surface of virtually all cells. IFNβcan bind to IFNAR2 alone, but can bind to <scene name='56/566498/Human_ifnar1/1'>IFNAR1</scene> only in | ||
the presence of IFNAR2. The strength of IFNβbinding to its | the presence of IFNAR2. The strength of IFNβbinding to its | ||
receptor is much higher when both subunits are present. | receptor is much higher when both subunits are present. | ||