4nj4: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4nj4|  PDB=4nj4  |  SCENE=  }}
+===Crystal Structure of Human ALKBH5===
-The entry 4nj4 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/ALKB5_HUMAN ALKB5_HUMAN]] Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m(6)A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m(6)A mRNA affects mRNA processing and export and is required for spermatogenesis.<ref>PMID:21264265</ref> <ref>PMID:23177736</ref>
-Authors: Aik, W.S., McDonough, M.A., Schofield, C.J.
+==About this Structure==
+[[4nj4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NJ4 OCA].
-Description: Crystal Structure of An Oxygenase In Complex with An Inhibitor
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Aik, W S.]]
+[[Category: McDonough, M A.]]
+[[Category: Schofield, C J.]]
+[[Category: Dioxygenase]]
+[[Category: Double-stranded beta helix]]
+[[Category: Jelly-roll motif]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Rna]]
+[[Category: Rna demethylase]]