4nuc: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4nuc|  PDB=4nuc  |  SCENE=  }}
+===Crystal structure of the first bromodomain of human BRD4 in complex with MS435 inhibitor===
+{{ABSTRACT_PUBMED_24144283}}
-The entry 4nuc is ON HOLD
+==Disease==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
-Authors: Plotnikov, A.N., Joshua, J., Zhou, M.-M.
+==Function==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
-Description: Crystal structure of the first bromodomain of human BRD4 in complex with MS435 inhibitor
+==About this Structure==
+[[4nuc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NUC OCA].
+==Reference==
+<ref group="xtra">PMID:024144283</ref><references group="xtra"/><references/>
+[[Category: Joshua, J.]]
+[[Category: Plotnikov, A N.]]
+[[Category: Zhou, M M.]]
+[[Category: Transcription]]
+[[Category: Transcription factor]]