Ferrochelatase: Difference between revisions
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<StructureSection load='2qd2' size='450' side='right' scene='Journal:JBIC:4/Heme_bound_ferro_open/3' caption=''> | <StructureSection load='2qd2' size='450' side='right' scene='Journal:JBIC:4/Heme_bound_ferro_open/3' caption=''> | ||
<StructureSection load='2qd2' size='450' side='right' scene=' | <StructureSection load='2qd2' size='450' side='right' scene='' caption=''> | ||
'''Ferrochelatase''' (FECH) catalyzes the last step in the formation of heme. FECH adds Fe+2 to protoporphyrin IX converting it to protoheme. The human FECH is a homodimer containing 2 similar domains and an iron-sulfur cluster. Defective FECH is the cause of porphyria. | '''Ferrochelatase''' (FECH) catalyzes the last step in the formation of heme. FECH adds Fe+2 to protoporphyrin IX converting it to protoheme. The human FECH is a homodimer containing 2 similar domains and an iron-sulfur cluster. Defective FECH is the cause of porphyria. | ||