2ra0: Difference between revisions

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OCA

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-[[Image:2ra0.jpg|left|200px]]<br /><applet load="2ra0" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2ra0.jpg|left|200px]]
-caption="2ra0, resolution 2.30&Aring;" />
-'''X-ray Structure of FXa in complex with 7-fluoroindazole'''<br />
+ {{Structure
+|PDB= 2ra0 |SIZE=350|CAPTION= <scene name='initialview01'>2ra0</scene>, resolution 2.30&Aring;
+|SITE= <scene name='pdbsite=AC1:Jnj+Binding+Site+For+Residue+A+1'>AC1</scene>
+|LIGAND= <scene name='pdbligand=JNJ:'>JNJ</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6]
+|GENE= F10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''X-ray Structure of FXa in complex with 7-fluoroindazole'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-RA0 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=JNJ:'>JNJ</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] Known structural/functional Site: <scene name='pdbsite=AC1:Jnj+Binding+Site+For+Residue+A+1'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RA0 OCA].
+RA0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RA0 OCA].
 ==Reference==
--fluoroindazoles as potent and selective inhibitors of factor Xa., Lee YK, Parks DJ, Lu T, Thieu TV, Markotan T, Pan W, McComsey DF, Milkiewicz KL, Crysler CS, Ninan N, Abad MC, Giardino EC, Maryanoff BE, Damiano BP, Player MR, J Med Chem. 2008 Jan 24;51(2):282-97. Epub 2007 Dec 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18159923 18159923]
+-fluoroindazoles as potent and selective inhibitors of factor Xa., Lee YK, Parks DJ, Lu T, Thieu TV, Markotan T, Pan W, McComsey DF, Milkiewicz KL, Crysler CS, Ninan N, Abad MC, Giardino EC, Maryanoff BE, Damiano BP, Player MR, J Med Chem. 2008 Jan 24;51(2):282-97. Epub 2007 Dec 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18159923 18159923]
 [[Category: Coagulation factor Xa]]
 [[Category: Homo sapiens]]
@@ Line 18: / Line 27: @@
 [[Category: blood coagulation]]
 [[Category: calcium]]
-[[Category: cleavage on pair of basic residues]]
+[[Category: cleavage on pair of basic residue]]
 [[Category: egf-like domain]]
 [[Category: gamma-carboxyglutamic acid]]
@@ Line 28: / Line 37: @@
 [[Category: zymogen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:45:44 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:34:01 2008''