2qtw: Difference between revisions

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[[Image:2qtw.jpg|left|200px]]<br /><applet load="2qtw" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qtw.jpg|left|200px]]
caption="2qtw, resolution 1.90&Aring;" />
 
'''The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain'''<br />
{{Structure
|PDB= 2qtw |SIZE=350|CAPTION= <scene name='initialview01'>2qtw</scene>, resolution 1.90&Aring;
|SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+B+1001'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+B+1'>AC2</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY=
|GENE= PCSK9, NARC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QTW is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+B+1001'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+B+1'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QTW OCA].  
2QTW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QTW OCA].  


==Reference==
==Reference==
The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain., Hampton EN, Knuth MW, Li J, Harris JL, Lesley SA, Spraggon G, Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14604-9. Epub 2007 Sep 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17804797 17804797]
The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain., Hampton EN, Knuth MW, Li J, Harris JL, Lesley SA, Spraggon G, Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14604-9. Epub 2007 Sep 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17804797 17804797]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: zymogen]]
[[Category: zymogen]]


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