Catabolite control protein: Difference between revisions

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[2jcg]], [[2hsg]] - BmCcpA – ''Bacillus megaterium'' <br />
*CcpA
[[1sxg]], [[1sxh]], [[1sxi]] – BmCcpA (mutant)  <br />
[[2o20]] - CcpA (mutant) – ''Streptococcus lactis'' <br />


===CcpA binary complex===
**[[2jcg]], [[2hsg]] - BmCcpA – ''Bacillus megaterium'' <br />
**[[2o20]] - CcpA (mutant) – ''Streptococcus lactis'' <br />


[[2oen]] - BmCcpA + phosphocarrier protein HPr  <br />
*CcpA binary complex
[[2fep]] - BsCcpA + phosphocarrier protein HPr – ''Bacillus subtilis''<br />


===CcpA ternary complex===
**[[2oen]] - BmCcpA + phosphocarrier protein HPr  <br />
**[[2fep]] - BsCcpA + phosphocarrier protein HPr – ''Bacillus subtilis''<br />


[[1rzr]] – BmCcpA + phosphocarrier protein HPr + DNA  <br />
*CcpA ternary complex
[[2nzu]] - BmCcpA + phosphocarrier protein HPr + glucose-6-phosphate  <br />
[[2nzv]] - BmCcpA + phosphocarrier protein HPr + fructose-1,6-diphosphate  <br />
[[1zvv]] – BsCcpA + catabolite repression Crh + DNA  <br />
[[3oqm]], [[3oqn]], [[3oqo]] - BsCcpA + phosphocarrier protein HPr + DNA<br />


**[[1rzr]] – BmCcpA + phosphocarrier protein HPr + DNA  <br />
**[[2nzu]] - BmCcpA + phosphocarrier protein HPr + glucose-6-phosphate  <br />
**[[2nzv]] - BmCcpA + phosphocarrier protein HPr + fructose-1,6-diphosphate  <br />
**[[1zvv]] – BsCcpA + catabolite repression Crh + DNA  <br />
**[[3oqm]], [[3oqn]], [[3oqo]] - BsCcpA + phosphocarrier protein HPr + DNA<br />
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 16:11, 19 November 2014

<StructureSection load='2fep' size='350' side='right' caption='Structure of catabolite control protein (grey) complex with Hpr (khaki) and sulfate (PDB entry 2fep)' scene=>

Catabolite control protein (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.

3D structures of catabolite control protein3D structures of catabolite control protein

Updated on 19-November-2014

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky