4mz3: Difference between revisions
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{{STRUCTURE_4mz3| PDB=4mz3 | SCENE= }} | |||
===Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant=== | |||
The entry | ==Disease== | ||
[[http://www.uniprot.org/uniprot/SCN4B_HUMAN SCN4B_HUMAN]] Romano-Ward syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SCN4B_HUMAN SCN4B_HUMAN]] Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation (By similarity). | |||
==About this Structure== | |||
[[4mz3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZ3 OCA]. | |||
[[Category: Das, S.]] | |||
[[Category: Petegem, F Van.]] | |||
[[Category: Extracellular]] | |||
[[Category: Ion conductance]] | |||
[[Category: Membrane protein]] | |||
Revision as of 10:34, 4 December 2013
Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutantCrystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant
DiseaseDisease
[SCN4B_HUMAN] Romano-Ward syndrome. The disease is caused by mutations affecting the gene represented in this entry.
FunctionFunction
[SCN4B_HUMAN] Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation (By similarity).
About this StructureAbout this Structure
4mz3 is a 2 chain structure. Full crystallographic information is available from OCA.