2q5o: Difference between revisions
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[[Image:2q5o.jpg|left|200px]] | [[Image:2q5o.jpg|left|200px]] | ||
'''X-ray structure of phenylpyruvate decarboxylase in complex with 3-deaza-ThDP and phenylpyruvate''' | {{Structure | ||
|PDB= 2q5o |SIZE=350|CAPTION= <scene name='initialview01'>2q5o</scene>, resolution 2.15Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPW:2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPW</scene>, <scene name='pdbligand=PPY:3-PHENYLPYRUVIC+ACID'>PPY</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylpyruvate_decarboxylase Phenylpyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.43 4.1.1.43] | |||
|GENE= ipdC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192 Azospirillum brasilense]) | |||
}} | |||
'''X-ray structure of phenylpyruvate decarboxylase in complex with 3-deaza-ThDP and phenylpyruvate''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2Q5O is a [ | 2Q5O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Azospirillum_brasilense Azospirillum brasilense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q5O OCA]. | ||
==Reference== | ==Reference== | ||
Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase., Versees W, Spaepen S, Wood MD, Leeper FJ, Vanderleyden J, Steyaert J, J Biol Chem. 2007 Nov 30;282(48):35269-78. Epub 2007 Sep 28. PMID:[http:// | Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase., Versees W, Spaepen S, Wood MD, Leeper FJ, Vanderleyden J, Steyaert J, J Biol Chem. 2007 Nov 30;282(48):35269-78. Epub 2007 Sep 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17905741 17905741] | ||
[[Category: Azospirillum brasilense]] | [[Category: Azospirillum brasilense]] | ||
[[Category: Phenylpyruvate decarboxylase]] | [[Category: Phenylpyruvate decarboxylase]] | ||
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[[Category: PPY]] | [[Category: PPY]] | ||
[[Category: TPW]] | [[Category: TPW]] | ||
[[Category: closed active site | [[Category: closed active site loop]] | ||
[[Category: lyase]] | [[Category: lyase]] | ||
[[Category: substrate complex]] | [[Category: substrate complex]] | ||
[[Category: symmetrical dimer of | [[Category: symmetrical dimer of dimer]] | ||
[[Category: thiamine diphosphate]] | [[Category: thiamine diphosphate]] | ||
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