Single stranded binding protein: Difference between revisions

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 DNA,  whereas modification of either lysine residues (with acetic anhydride) or tryptophan
 residues (with N-bromosuccinimide) led to complete loss of binding activity <ref>PMID: 2087220</ref>.
-The two tryptophan residues involved in DNA binding are Trp40 and Trp54, which was
-determined by mutagenesis. One more binding site was determined by site-specific mutagenesis.
-When His55 is substituted with Leu it decreases binding affinity. All of these residues
-are found in a hydrophobic region, which is suitable for nucleotide base interactions.
 ==SSB-Protein Interactions==