Single stranded binding protein: Difference between revisions
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==SSB-Protein Interactions== | ==SSB-Protein Interactions== | ||
When DNA binds SSB, most of the molecule loses flexibility. But three of the phenylalanines (147, 171, 177) in the COOH terminal domain remain flexible, even after DNA binding. It is questioned whether the COOH terminus has anything to do with protein binding. | |||
It is believed that Gly15 may play an important role in binding the RecA protein. Mutations in Gly15 have | It is believed that Gly15 may play an important role in binding the RecA protein. Mutations in Gly15 have | ||
extreme effects on recombinational repair. SSB has also been thought to bind with exonuclease I, DNA polymerase II, | extreme effects on recombinational repair. SSB has also been thought to bind with exonuclease I, DNA polymerase II, | ||